Researchers from Taipei Veterans General Hospital, Taipei, Taiwan, have found that persons with insomnia had more than twice the risk of a future heart attack and were nearly as likely to have a stroke compared with those without sleeping problems.
They studied a nationwide database (N=43,180) of those 45 years and older with insomnia and compared them with a similar group without insomnia. During an average follow-up of four years (4.4 +/-2.7), there were 424 acute myocardial infarction (AMI) events (0.98%) and 3307 stroke events (7.66%). The insomnia group had a higher incidence of AMI (1.63% vs 0.76%, P
<0.001) and stroke (11.18% vs 6.47%, P
Additionally, Cox proportional hazard regression model analysis showed that insomnia was independently associated with risk of developing future AMI (hazard ratio [HR] 2.30; 95% confidence interval [CI], 1.90 to 2.79, P
<0.0001), stroke (HR 1.99; 95% CI, 1.86 to 2.14, P
<0.001), and composite events (HR 2.04; 95% CI, 1.91 to 2.18, P
<0.001) after adjusting for age, gender, and co-morbidities.