Researchers Find that Endometrial Cancer Survivors’ Unhealthy Lifestyles Increase Risk of Premature Death

   According to a paper presented at the American College of Obstetricians and Gynecologists' 58th Annual Clinical Meeting in San Francisco, endometrial cancer (EC) survivors have unhealthy lifestyles that put them at risk for premature death.

   Vivian E. von Gruenigen, MD, and colleagues at Summa Health System in Akron, Ohio, noted that EC survivors are already at risk for premature death. The purpose of the study was to examine lifestyle behaviors in EC survivors that contribute to their morbidity.

   Patients diagnosed with early stage (I or II) EC with a body mass index (BMI) greater than 25 were eligible. Patients completed questionnaires on comorbidities, physical activity (PA), and fruit and vegetable intake. Lifestyle behaviors were compared with American Cancer Society (ACS) guidelines for cancer survivors (150 minutes per week of moderate to strenuous PA, five servings of fruit and vegetables per day, and no smoking).

   One hundred six patients were enrolled. Their mean age was 56.7 BMI was 39.1; adjuvant radiation treatment had occurred with 38%.

   Forty percent of patients had hypertension, 39% osteoarthritis, 33% metabolic syndrome, and 24% type II diabetes. Ninety-four percent of patients had abdominal obesity (waist circumference greater than 35 inches), with a median waist circumference of 41.8 inches; 75% had waist/hip ratios greater than 0.80. Ninety percent of patients were at very or extremely high disease risk for development of type II diabetes, hypertension, and cardiovascular disease, according to national guidelines. Eighty-percent reported no strenuous PA and 61% no moderate PA; only 21% were meeting PA guidelines. Only 18% reported consuming five or more servings of fruit and vegetables per day,  and the median was 2.6 servings per day. While 79% of patients were nonsmokers. overall only two percent of patients met all three ACS lifestyle guidelines.

   Dr. von Gruenigen and colleagues concluded that EC survivors have unhealthy lifestyles that put them at risk for premature death.